Best Fat Burner Supplements in 2022: Our Top 5 Picks

Best Fat Burner Supplements

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Diet, sleep, and exercise are the foundation of every good weight loss program. People who get results are those who prioritize these fundamentals before considering a fat burner supplement.

Having said that, we could all occasionally use some help. Fat burners are food supplements used to assist you in the process of getting leaner and healthier. They are typically marketed as a magic solution to getting your dream body. But we all know there are no shortcuts to success in fitness.

Before we get to our recommended list of weight loss supplements, it’s important to note that these products haven’t been proven to burn fat. It is the ingredients inside these products that have clinical evidence backing their safety and effectiveness for weight loss.

A high-quality fat burner supplement gives your body a range of clinically dosed vitamins, minerals, and herbal extracts which have been shown to raise your energy levels, increase metabolism, curb appetite, and boost fat breakdown in the body, among other benefits.

The following fat burners have all been roadtested by experts to ensure they’re completely safe and clear of iffy ingredients. Our criteria include:

  • 100% natural ingredient profile
  • Reliable, lean physique results
  • Clean energy
  • Sugar & salt craving reduction
  • Healthy concentration & mood
  • Company reputation
  • Safe for everyday use

The following products also have the ability to boost your overall performance levels, which can be useful when you’re under calorie restriction.

Each fat burner uses different ingredients in different dosages. So each one will give you different results. After reviewing over 40 fat burner supplements in the past year alone, we’ve narrowed down our choice to the 5 very best options on the market right now.

Our Choice: Five of The Best Weight Loss Supplements

Instant Knockout

  • Formulated for Pro Athletes

  • Elevate metabolism 

  • Reduce appetite

  • Fast-acting fat burn

  • Excellent reviews

Hourglass Fit

  • Specifically developed for women

  • Achieve toned muscles

  • Gain definition

  • Stimulant-free ingredient profile

  • Check price:

Burn Lab Pro

  • Cleanest quality stim-free fat burner

  • 100% transparent & free from fillers

  • Used by UFC Bantamweight Champ

  • Patented nutrition technology

  • Excellent bulk-buy deals

  • Check price:

Hunter Burn

  • More ingredients

  • Larger doses & servings 

  • Potent hunger control

  • Premium-grade supplement

  • Maximum impact formula

  • Check price:


  • 40mg of Pure CBD isolate per capsule

  • Works to enhance your exercise

  • cGMP approved and safety controlled

  • Promotes fat 'browning'

  • May improve your sleep & mood

  • Check price:

What is a Weight Loss Supplement?

As we explained, weight loss supplements are over-the-counter food products typically consisting of different nutrients and herbs which have been shown to affect weight loss in one way or another.

For example, a combination of certain plant extracts within a supplement may produce a thermogenic effect, making your metabolism more efficient at burning calories.

So, if you’ve been struggling to stay below your daily caloric maintenance, a fat burner can help you burn those extra calories – giving you the edge needed to finally start getting results.

  • Not only that, there are ingredients in fat burners that work as natural appetite suppressants. For example, fibrous plants like Glucomannan are considered the industry-leading appetite suppressants due to their ability to expand in your stomach and make you feel fuller. This results in fewer calories being consumed overall.

Some supplements also use clinical amounts of stimulants such as caffeine anhydrous. The reason is that stimulants make you more energized, boost your metabolism further, and suppress your appetite. When dosed correctly and taken with optimal serving frequency, natural stimulants can be one of the safest and most effective ways to accelerate weight loss. But there are also exceptions, like Yohimbine and Bitter Orange – we’ll warn you of these in our reviews.

Caffeineated fat burners represented by roasted and raw beans

As we’ve repeated, plant extracts are also common ingredients you’ll find in fat burners. Some of these have robust human evidence, and, some do not! It is a good idea to research all the ingredients in a supplement yourself to really learn about how they work in your body.

The Top 5 Fat Burner Supplements in 2022

Now that we’ve covered the basics about what you should expect from a fat burner supplement, let’s continue toward our top 5 final contenders for 2022.

1. Instant Knockout CUT – Best Overall

Instant Knockout CUT is manufactured and sold by a specialist supplement company called Roar Ambition. It is produced in both the USA and UK and ships worldwide.

Instant Knockout Cut

A vegan-friendly supplement, Instant Knockout was originally designed for use by professional MMA coaches and fighters to help them cut weight before a big event. Due to its success and impressive results, Instant Knockout was later released to the general public. It remains one of the highest-rated fat burners with excellent reviews from countless testimonials online.

Some of the people who endorse Instant Knockout include Greg Jackson, one of the world’s most renowned MMA coaches, as well as Diego Sanchez, a professional UFC fighter.

Key advantages of Instant Knockout Cut:

  • Cut fat quickly like a pro-MMA fighter
  • Helps you to lose fat, not muscle
  • A strong thermogenic and appetite suppressant

Among Instant Knockout’s ingredients are well-studied inclusions such as Cayenne Pepper Extract, Green Tea, and a powerful dietary fiber called Konjac Root (Glucomannan). This particular ingredient is one of the best natural appetite suppressants available – it can swell up to 100x its size to provide long-lasting, effective hunger control.

Instant Knockout Cut also features a clinically dosed 75mg of caffeine per capsule (and 300mg per daily serving). Alongside it is L-Theanine, an amino acid from green tea which enhances caffeine’s benefits and reduces its negative effects, such as jitters.

Official website:

The rest of the ingredients in Instant Knockout include vitamins B6, B12, and D3, which further boost your metabolic speed as well as improve the rate of fat breakdown. You’ll also find Green Coffee Bean Extract in Instant Knockout, which helps to stabilize your blood sugar levels; reducing food cravings in the process. Black Pepper Extract is added to tie Instant Knockout together – enhancing the absorption and efficacy of other ingredients in the formula.

Here is the full Instant Knockout Cut ingredients list:

Instant Knockout CUT Ingredients
Our Instant Knockout Cut bottle.

In each transparent, fist-shaped bottle you will find 120 capsules, which equals a month’s supply.

Interestingly, Instant Knockout has a dosage of 1 capsule, 4 times per day. This is a really clever way to dose a fat burner – it enables the beneficial ingredients to circulate in your system for longer.


  • Great value
  • Achieve a leaner physique
  • Premium formula with clinically dosed ingredients
  • Trusted by pro fighters and trainers
  • Safe and natural ingredient profile
  • Excellent bulk-buy deals with worldwide shipping


Instant Knockout Is Available On The Manufacturer’s Website

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2. Hourglass Fit – The Best-Rated Women’s Fat Burner

Coming in 2nd place is Hourglass Fit, an exciting diet pill formulated for women who’re looking to achieve the “Hourglass Figure”. More specifically, a healthy body with toned muscles and minimum on body fat.

Hourglass Fit

The good news is, Hourglass Fit works impressively for pretty much everyone. When you look past the marketing, there is not a massive difference between male and female needs when it comes to fat burners. It will work just the same in both cases.

Key advantages of Hourglass Fit:

  • Helps you to lose fat around your waist and get a sexy Hourglass physique
  • Powerful caffeine free formula
  • Contains a massive 3g of the proven appetite suppressant glucomannan 

What stood out to us about Hourglass Fit is not only its appetite-curbing effect but also the ability to burn body fat at the same time. In other words, Hourglass Fit helps you consume fewer calories throughout the day, while also reducing belly and waist fat with its natural thermogenic ingredients.

  • Increase energy without stimulants
  • Tone up for a lean physique
  • Burns fat while controlling hunger

Official website:

Hourglass Fit is packed with studied and potent fat-burning compounds. For example, you will find a healthy dosage of cayenne extract, an evidence-backed thermogenic that heats up your body, boosts your metabolism, and makes you break down fat faster. There is also 3000mg of glucomannan, one of the best appetite suppressants on the market which works to keep your hunger at bay between meals.

The appetite-curbing effect of Hourglass Fit is further augmented by 5-HTP, a brain molecule that is shown to improve mood and block hunger-triggering hormones, helping you to stay below your calorie limit. The formula also contains a range of essential nutrients such as B6, B12, and zinc to keep your hormones in balance for optimal fat burning.

Here is the full ingredient list:

Hourglass Fit Ingredients

Each bottle of Hourglass Fit contains 120 capsules, lasting 30 days. To get the maximum effects throughout the day, you should take one capsule, four times per day. Again, this is an excellent serving schedule, just like with Instant Knockout.


  • Burn fat and reveal a toned figure
  • Effective reduction of hunger cravings with a high dose of glucomannan
  • Completely free of caffeine or other stimulants
  • Works for both genders, although the nutrients are specifically dosed for women’s metabolic needs


  • Only sells directly from the manufacturer
  • Some people will want a stronger stimulant “kick”

Hourglass Fit Is Available On The Manufacturer’s Website

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3. Burn Lab Pro – Cleanest Quality Non-Caffenianted Fat Burner

Burn Lab Pro is a vegan, stim-free fat burner with one of the cleanest formulas we’ve seen.

Burn Lab Pro

Developed by the specialist supplement company from the U.K., Opti-Nutra. Burn Lab Pro is low on caffeine, but still as effective as any premium fat burner.

Among the ingredients in Burn Lab Pro you will find the essential trace mineral chromium, which helps to keep your blood sugar levels in balance. This in turn may contribute to a reduction in sugar cravings.

Cayenne pepper and Coleus Forskohlii are two other powerful additions to the formula, with the latter proving to be a potent fat-burning agent in studies. Coleus Forskohlii works by stimulating the enzymes in your body to break down fat quicker.

Another key ingredient that separates Burn Lab Pro from most fat burners is HMB calcium. This carefully chosen compound works by inhibiting the enzymes in your body which are responsible for muscle breakdown. You burn fat, but not the hard-earned muscle along with it.

Burn Lab Pro’s ingredients as a whole are patented and some of the highest-quality forms we’ve seen. The ingredient dosages are on the lighter side, making Burn Lab Pro healthy for daily use.

Who would we say Burn Lab Pro is especially for? It’s for you if you’re looking to maintain your lean muscle mass while burning fat, as well as if you are sensitive to stimulants or if you simply want to avoid any unnecessary fillers or other synthetic ingredients – none of those are in Burn Lab Pro!

Official website:

Here is the full ingredient list:

Burn Lab Pro Ingredients

If you’re someone who loves to do intermittent fasting (IF) and train on an empty stomach, Burn Lab Pro could be for you especially, because it enhances the effects of fasted training on your body composition while preventing muscle breakdown.

A Burn Lab Pro bottle has 90 capsules, with the recommended dosage of 2-4 capsules before working out for maximum benefit.


  • Cleanest-quality formula available
  • Stimulant-free
  • Using patented, highly standardized compounds for stable, long-lasting effects
  • Protects from muscle loss
  • Works amazingly well with intermittent fasting


  • The energy “kick” is not the same as with stimulant-containing fat burners
  • Not as good in the appetite suppression department as some other options on the list

Burn Lab Pro Is Available On The Manufacturer’s Website

Get Prices

4. Hunter Burn

Burn by Hunter Evolve is our fourth product on this list, but it is by no means inferior. In fact, Hunter Burn boasts the largest ingredient doses and serving sizes we’ve seen in any fat burner.

Hunter Burn

This is the key selling point of the Hunter brand – a premium selection of products for customers who want the absolute best and don’t mind paying for it. This fat burner can certainly “walk the talk” when it comes to being top-of-the-line quality.

Key advantages of Hunter Burn:

  • Bigger dosed for faster results – 180 capsules per bottle
  • The highest quality ingredients available, in large doses
  • For consumers looking for the best product on the market

In a nutshell, Hunter burn is a weight loss supplement for people who want the very best ingredients, at the maximum effective amounts, for potentially more substantial results.

Official website:

Its premium price reflects this, which is why it’s a bit lower on our list. We understand some people might prefer a less expensive option. That said, Hunter Burn offers more of everything, so it’s definitely worth the money if you’re able to afford it.

Ingredients in Hunter Burn

Hunter Burn features the key ingredients you’ll find in other highest-ranked products, but at much larger doses. For example, Hunter Burn contains matcha green tea, an expensive and highly-concentrated variant of the green tea extract. The advantage is this type of green tea is three times more potent – and it could help burn calories even faster. [1]

Hunter Burn also includes Konjac Root, which helps stave off hunger throughout the day. To top it off, 3,000IU of vitamin D3 works to optimize your hormones for faster weight loss, but also muscle gain. [2]

Here is the full ingredient list:

Hunter Burn Ingredients

Hunter Burn contains a generous 180 capsules per bottle. Each daily serving is six capsules, giving you 30 servings per container. The directions for use say you should take 2 capsules with a glass of water, three times per day before your meals.

These large servings keep you supplied with potent fat-burning compounds and it is the key advantage Hunter Burn has over other products on the market.


  • Higher doses for maximum results
  • More of each key compound
  • Helps burn fat and reduce appetite as a part of a healthy lifestyle
  • Premium-grade product


  • Only available direct from the manufacturer
  • Steep price

Burn by Hunter Evolve Is Available On The Manufacturer’s Website

Get Prices

5. ShredCBD – The Best CBD-Based Weight Loss Supplement


ShredCBD is an innovative, side-effect-free solution to burning unwanted fat and feeling healthier. CBD plays a vital role in your body’s endocannabinoid system (ECS). Which is why supplementation is so effective. It is completely different from any other product on sale today.

CBD helps you “shred down” in 5 main ways:

  1. Triggers fat browning to stimulate the body to use fat as fuel
  2. Supports insulin sensitivity to prevent unwanted weight gain
  3. Substantially lowers cortisol, a stress hormone that promotes fat accumulation
  4. Improves mental well-being and sleep quality
  5. Reduces appetite and calorie consumption by interacting with brain’s ECS receptors

ShredCBD contains pure hemp isolate as its CBD, meaning it’s below 0.1% THC. This makes it non-psychoactive (doesn’t make you high), and completely legal in the USA and many other countries in the world.

Official website:

In addition to CBD, the formula contains a synergistic combination of Green Tea and Garcinia Cambogia Extract to enhance the fat breakdown effects of CBD. Green Tea and Garcinia also provide healthful antioxidants to boost your immunity and keep you feeling leaner.

ShredCBD Ingredients
ShredCBD’s ingredient label.

What makes ShredCBD stand out in our eyes, is that it is just as effective for sleep, mood, and overall quality of life enhancement, as it is for weight loss. It is a kind of supplement you can use together with other supplements in your stack for all-around wellness support.

We’ve found ShredCBD to be a top-quality product that even after a couple of days led to some noticeable improvements in appetite, focus, and mood.

In terms of weight loss, you can expect ShredCBD to start showing results after around 30 days. Especially if you use CBD’s power to exercise and focus on a nutrient-packed diet.

Effects over 2-6 weeks with ShredCBD:

  • Good amount of wight loss (as much as any stim-free fat burner)
  • Less desire to snack
  • More consistent energy throughout the day, without highs and lows
  • Most notable improvements in sleep and daily focus

ShredCBD is free of stimulants, which makes it a good choice if you don’t tolerate caffeine.

The Good

  • Industry-leading dose of 40mg of pure CBD Isolate per serving (1200mg per bottle)
  • CBD alone offers more benefits than many fat burner blends
  • 50mg of Garcinia+Green Tea to augment appetite-controlling and energy-enhancing effects
  • Free and Fast shipping in the USA
  • Free 24-page weight loss e-Book ($10 value, according to the manufacturer)

The Bad

  • Only sells in the USA
  • Premium price due to costly CBD isolate manufacturing

ShredCBD Is Available On The Manufacturer’s Website

Get Prices

Final Thoughts on The Best Fat Burners in 2022

With a little research, you can easily find the ideal fat burning supplement for yourself. It is important to know that fat burner supplements, when using high-quality ingredients in studied dosages, are very safe and unlikely to cause side effects.

Our personal preference is without question Instant Knockout CUT. There is a reason why it’s been among market-leading fat burner supplements ever since its release in 2015. It is a tried and tested formula that works. Instant Knockout is not some outdated supplement, either. Its manufacturers consult with nutritionists and fitness experts to keep Instant Knockout updated in accordance to the latest weight loss research.

Hourglass Fit is the ideal weight loss supplement for women who struggle with appetite control and low energy during the day.

Burn Lab Pro is another solid option if you are sensitive to stimulants like caffeine. It works to enhance fat burning in a light and safe way, while also being highly effective at preserving muscle when you train on an empty stomach.

References, Literature, and Sources

  1. Weiss DJ, Anderton CR. Determination of catechins in matcha green tea by micellar electrokinetic chromatography. J Chromatogr A. 2003 Sep 5;1011(1-2):173-80. doi: 10.1016/s0021-9673(03)01133-6. PMID: 14518774. (source)
  2. Caitlin Mason, Liren Xiao, Ikuyo Imayama, Catherine Duggan, Ching-Yun Wang, Larissa Korde, Anne McTiernan, Vitamin D3 supplementation during weight loss: a double-blind randomized controlled trial, The American Journal of Clinical Nutrition, Volume 99, Issue 5, May 2014, Pages 1015–1025,

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