Best Fat Burner Supplements in 2022: Our Top 5 Picks

Your complete guide to some of the best natural weight loss supplements on the market today.

Best Fat Burner Supplements

A controlled diet and regular exercise should always be your starting point before considering a fat burner supplement. Getting lean and burning unwanted fat takes discipline, patience, and unwavering commitment.

Note: We’ve updated this guide with the latest information and supplements. We currently rate Instant Knockout CUT (for men and women) and Hourglass Fit (for women) as two of the most effective options on the market.

Weight loss supplements have a bit of an iffy reputation, mainly because they are often marketed as a magic solution to help you sculpt your dream body. We all know that there are no shortcuts to success in life, especially when it comes to health and fitness.

Before we get to our list of the current “top fat burners”, you should be aware that most of the supplements featured on this page are not magic pills – and they are not proven to do all the hard work on their own.

Editor’s comment: The content on this website is informative in nature – it should not be taken as medical advice. Our guides, reviews and the products featured in them are not meant for use as a diagnosis, treatment, or prevention of health conditions. Always check with a qualified physician before making any changes to your diet, exercise, lifestyle, and supplement regimen.

However, what quality fat burner supplements can do is supply a range of ingredients such as nutrients, stimulants, and herbal extracts, each of which is backed by evidence to support weight loss in one way or another – be it through appetite suppression or increasing your metabolism.

The following fat burners have all been roadtested for safety and effectiveness, with all of them also being 100-percent natural and vegan-friendly.

Our Pick: Five of The Best Weight Loss Supplements

Instant Knockout

  • Formulated for Pro Athletes

  • Elevate metabolism 

  • Reduce appetite

  • Fast-acting fat burn

  • Excellent reviews

Hourglass Fit

  • Specifically developed for women

  • Achieve toned muscles

  • Gain definition

  • Stimulant-free ingredient profile

  • Check price:

Burn Lab Pro

  • Cleanest quality stim-free fat burner

  • 100% transparent & free from fillers

  • Used by UFC Bantamweight Champ

  • Patented nutrition technology

  • Excellent bulk-buy deals

  • Check price:

Hunter Burn

  • More ingredients

  • Larger doses & servings 

  • Potent hunger control

  • Premium-grade supplement

  • Maximum impact formula

  • Check price:


  • 40mg of Pure CBD isolate per capsule

  • Works to enhance your exercise

  • cGMP approved and safety controlled

  • Promotes fat 'browning'

  • May improve your sleep & mood

  • Check price:

What Exactly is a Weight Loss Supplement?

As we just mentioned, so-called “weight loss pills” or “fat burners” are supplements that usually consist of plant extracts, vitamins and minerals, and other ingredients which have potential benefits.

Supplements are not meant to replace a varied diet, regular sleep, and daily exercise, but they can make up for some of the potential ‘holes’ in certain nutrients.

For example, many fat burner supplements contain essential nutrients which assist in supporting a number of important bodily processes.

Some supplements also contain stimulants such as caffeine. The reason is that stimulants help you feel more energized, increase your metabolism, and nudge you to be more active (and therefore burn more calories). However, you are probably aware that there is a fine line between feeling the benefits of caffeine and overdoing it.

Caffeineated fat burners represented by roasted and raw beans

Plant or herbal extracts are also common additions to supplements of this category. Some of these ingredients have solid research behind them, and some, quite frankly, do not. It is a smart idea to learn about each ingredient yourself to check out some of the studies before committing to a supplement.

So to recap, the main ingredient groups you will normally find in a high-quality fat burner supplement are:

  • Nutrients – such as B vitamins, chromium, and Zinc
  • Stimulants – including caffeine
  • Herbal extracts – such as Cayenne Pepper, Green Coffee Bean, Green Tea, and Coleus Forskohlii

The Top 5 Fat Burner Supplements in 2022

So, with the basics out of the way, let’s now continue towards our pick of the best fat burner supplements currently on sale to help support your weight loss goals.

Editor’s comment: The health claims about the ingredients featured in this guide are authorized at the EU Register at the moment of writing.

All five of the supplements found on this list contain at least some essential vitamins and minerals, which work to support a variety of important functions in the body.

The products on this list are all 100% natural and free from any questionable or banned substances. Our team has trialed each of these supplements for at least 30 days to get a full picture of their effectiveness and safety.

We’ve also only featured supplements that have clear ingredient labels free from questionable proprietary blends.

This means that you can clearly see the doses of each ingredient on the labels, enabling you to know exactly what is inside the capsules.

1. Instant Knockout CUT – Best Overall

Instant Knockout CUT is manufactured and sold by a specialist supplement company called Roar Ambition. It is produced in both the USA and UK and ships worldwide.

Instant Knockout Cut

A vegan-friendly supplement, Instant Knockout was originally designed for use by professional MMA coaches and fighters to help them cut weight before a big event. It remains one of the highest-rated fat burners with excellent reviews from countless testimonials online.

Some of the people who endorse Instant Knockout include Greg Jackson, one of the world’s most renowned MMA coaches, as well as Diego Sanchez, a professional UFC fighter.

Key advantages of Instant Knockout Cut:

  • Cut fat quickly like a pro MMA fighter
  • Helps you to lose fat, not muscle
  • A strong thermogenic and appetite suppressant

Among Instant Knockout’s ingredients are well-studied inclusions such as Cayenne Pepper Extract, Green Tea, and a powerful dietary fiber called Konjac Root (Glucomannan). This particular ingredient is one of the best natural appetite suppressants available – it can swell up to 100x its size to provide long-lasting, effective hunger control.

Instant Knockout Cut also features a clinically dosed 75mg of caffeine per capsule (and 300mg per daily serving). It also includes a dose of L-Theanine, an amino acid from tea leaves which works awesomely in enhancing caffeine’s benefits while smoothening out the “jitters”.

Official website:

Other ingredients in the Instant Knockout’s formula include the essential vitamins B6, B12, and D3, all of which contribute to enhanced energy metabolism and the reduction of fatigue. It also features Green Coffee Bean Extract which stabilizes blood sugar levels – diminishing cravings by extension. Black Pepper Extract is added to tie Instant Knockout together – enhancing the absorption and efficacy of other ingredients in the formula.

Here is the full Instant Knockout Cut ingredients list:

Instant Knockout CUT Ingredients
Our Instant Knockout Cut bottle.

In each transparent, fist-shaped bottle you will find 120 capsules, which equals a month’s supply.

Interestingly, Instant Knockout has a dosage of 1 capsule, 4 times per day. This is a really clever way to dose a fat burner – it enables the beneficial ingredients to circulate in your system for longer.


  • Great value
  • Achieve a leaner physique
  • Premium formula with clinically dosed ingredients
  • Trusted by pro fighters and trainers
  • Safe and natural ingredient profile
  • Excellent bulk-buy deals with worldwide shipping


Instant Knockout Is Available On The Manufacturer’s Website

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2. Hourglass Fit – The Best-Rated Women’s Fat Burner

Coming in 2nd place is Hourglass Fit, a weight loss supplement that has been designed specifically for women who’re looking to achieve the ‘Hourglass Look.” Namely, a toned, shaped physique with attractive muscle and minimum on body fat.

Hourglass Fit
Our Hourglass Fit bottle.

The good news is, Hourglass Fit works for anyone. When you look past the marketing, it’s clear that there is not a lot of difference between male and female requirements as far as fat burners are concerned. It will work just the same in both cases.

Key advantages of Hourglass Fit:

  • Helps you to lose fat around your waist and get a sexy Hourglass physique
  • Powerful caffeine free formula
  • Contains a massive 3g of the proven appetite suppressant glucomannan 

What stood out about Hourglass Fit to us the most is its excellent ability to control your appetite and target fat at the same time. With this two-pronged approach, Hourglass Fit helps you lower your caloric intake by eating less food, and reduce belly and waist fat thanks to the potent thermogenic ingredients (more below).

  • Increase energy without stimulants
  • Tone up for a lean physique
  • Burns fat while controlling hunger

Official website:

Hourglass Fit contains a range of potent fat-burning ingredients. For instance, you will find 3,0000IU glucomannan, the same natural appetite suppressant from Instant Knockout but an even higher dose. This helps to stop you from getting constant hunger cravings between meals. The appetite suppressing effects are further augmented with the addition of 5-HTP in Hourglass Fit’s formula. 5-HTP is a natural precursor to serotonin, a brain chemical which is shown to improve mood and offset hunger-triggering hormones, helping you to control your calorie intake.

Hourglass Fit also contains cayenne pepper, a science-backed thermogenic that works to heat up your body, elevate your metabolism and help you break down more fat in less time. It also contains a range of essential nutrients including vitamins B6 & B12, and zinc.

Here is the full ingredient list:

Hourglass Fit Ingredients

Each bottle of Hourglass Fit contains 120 capsules, lasting 30 days. To get the maximum effects throughout the day, you should take one capsule, four times per day. Again, this is an excellent serving schedule, just like with Instant Knockout.


  • Burn fat and reveal a toned figure
  • Effective reduction of hunger cravings with a high dose of glucomannan
  • Completely free of caffeine or other stimulants
  • Works for both genders, although the nutrients are specifically dosed for women’s metabolic needs


  • Only sells direct from the manufacturer
  • Some people will want a stronger stimulant “kick”

Hourglass Fit Is Available On The Manufacturer’s Website

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3. Burn Lab Pro – Cleanest Quality Non-Caffenianted Fat Burner

Burn Lab Pro is a vegan, stim-free supplement with a clear and clean ingredients formula.

Burn Lab Pro

Developed by Opti-Nutra, Burn Lab Pro does not contain any caffeine. However, despite being a low stimulant option, we’ve found Burn Lab Pro to work just as impressively as any caffeinated fat burner on this list.

Among the ingredients, we have the essential trace mineral chromium, which contributes to the maintenance of healthy blood sugar levels to improve appetite control.

Cayenne Pepper is another key player in the formula, along with a powerful addition of Coleus Forskohlii, the latter of which works to enhance the enzymes in your body which are responsible for increasing fat burn.

What’s more, Burn Lab Pro contains a rarely seen ingredient – HMB calcium. It is specifically included to protect muscle from breakdown. HMB works by blocking the enzymes which trigger muscle wasting due to hard training or calorie restriction.

On the whole, Burn Lab Pro has one of the cleanest-quality ingredient lists we’ve seen in any weight loss supplement.

Official website:

Here is the full ingredient list:

Burn Lab Pro Ingredients

Burn Lab Pro’s website emphasized that this product is ideal for those who practice training on an empty stomach, also known as “fasted” training. Thanks to the inclusion of HMB and Coleus Forskohlii, Burn Lab Pro enhances the positive effects of intermittent fasting (IF) on your body composition.

Each Burn Lab Pro bottle has 90 capsules, with the recommended serving size of 2-4 capsules before a workout for maximum benefit.


  • Cleanest-quality formula available
  • Stimulant-free
  • Using patented, highly standardized compounds for stable, long-lasting effects
  • Protects from muscle loss
  • Works amazingly well with intermittent fasting


  • The energy “kick” is not the same as with stimulant-containing fat burners
  • Not as good in the appetite suppression department as some other options on the list

Burn Lab Pro Is Available On The Manufacturer’s Website

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4. Hunter Burn

Burn by Hunter Evolve is our fourth product on this list, but it is by no means inferior. In fact, Hunter Burn boasts the largest ingredient doses and serving sizes we’ve seen in any fat burner.

Hunter Burn

This is the key selling point of the Hunter brand – a premium selection of products for customers who want the absolute best and don’t mind paying for it. This fat burner can certainly “walk the talk” when it comes to being top-of-the-line quality.

Key advantages of Hunter Burn:

  • Bigger dosed for faster results – 180 capsules per bottle
  • The highest quality ingredients available, in large doses
  • For consumers looking for the best product on the market

In a nutshell, Hunter burn is a weight loss supplement for people who want the very best ingredients, at the maximum effective amounts, for potentially more substantial results.

Official website:

Its premium price reflects this, which is why it’s a bit lower on our list. We understand some people might prefer a less expensive option. That said, Hunter Burn offers more of everything, so it’s definitely worth the money if you’re able to afford it.

Ingredients in Hunter Burn

Hunter Burn features the key ingredients you’ll find in other highest-ranked products, but at much larger doses. For example, Hunter Burn contains matcha green tea, an expensive and highly-concentrated variant of the green tea extract. The advantage is this type of green tea is three times more potent – and it could help burn calories even faster. [1]

Hunter Burn also includes Konjac Root, which helps stave off hunger throughout the day. To top it off, 3,000IU of vitamin D3 works to optimize your hormones for faster weight loss, but also muscle gain. [2]

Here is the full ingredient list:

Hunter Burn Ingredients

Hunter Burn contains a generous 180 capsules per bottle. Each daily serving is six capsules, giving you 30 servings per container. The directions for use say you should take 2 capsules with a glass of water, three times per day before your meals.

These large servings keep you supplied with potent fat-burning compounds and it is the key advantage Hunter Burn has over other products on the market.


  • Higher doses for maximum results
  • More of each key compound
  • Helps burn fat and reduce appetite as a part of a healthy lifestyle
  • Premium-grade product


  • Only available direct from the manufacturer
  • Steep price

Burn by Hunter Evolve Is Available On The Manufacturer’s Website

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5. ShredCBD – The Best CBD-Based Weight Loss Supplement


ShredCBD is an innovative, side-effect-free solution to burning unwanted fat and feeling healthier. CBD plays a vital role in your body’s endocannabinoid system (ECS). Which is why supplementation is so effective. It is completely different from any other product on sale today.

CBD helps you “shred down” in 5 main ways:

  1. Triggers fat browning to stimulate the body to use fat as fuel
  2. Supports insulin sensitivity to prevent unwanted weight gain
  3. Substantially lowers cortisol, a stress hormone that promotes fat accumulation
  4. Improves mental well-being and sleep quality
  5. Reduces appetite and calorie consumption by interacting with brain’s ECS receptors

ShredCBD contains pure hemp isolate as its CBD, meaning it’s below 0.1% THC. This makes it non-psychoactive (doesn’t make you high), and completely legal in the USA and many other countries in the world.

Official website:

In addition to CBD, the formula contains a synergistic combination of Green Tea and Garcinia Cambogia Extract to enhance the fat breakdown effects of CBD. Green Tea and Garcinia also provide healthful antioxidants to boost your immunity and keep you feeling leaner.

ShredCBD Ingredients
ShredCBD’s ingredient label.

What makes ShredCBD stand out in our eyes, is that it is just as effective for sleep, mood, and overall quality of life enhancement, as it is for weight loss. It is a kind of supplement you can use together with other supplements in your stack for all-around wellness support.

We’ve found ShredCBD to be a top-quality product that even after a couple of days led to some noticeable improvements in appetite, focus, and mood.

In terms of weight loss, you can expect ShredCBD to start showing results after around 30 days. Especially if you use CBD’s power to exercise and focus on a nutrient-packed diet.

Effects over 2-6 weeks with ShredCBD:

  • Good amount of wight loss (as much as any stim-free fat burner)
  • Less desire to snack
  • More consistent energy throughout the day, without highs and lows
  • Most notable improvements in sleep and daily focus

ShredCBD is free of stimulants, which makes it a good choice if you don’t tolerate caffeine.

The Good

  • Industry-leading dose of 40mg of pure CBD Isolate per serving (1200mg per bottle)
  • CBD alone offers more benefits than many fat burner blends
  • 50mg of Garcinia+Green Tea to augment appetite-controlling and energy-enhancing effects
  • Free and Fast shipping in the USA
  • Free 24-page weight loss e-Book ($10 value, according to the manufacturer)

The Bad

  • Only sells in the USA
  • Premium price due to costly CBD isolate manufacturing

ShredCBD Is Available On The Manufacturer’s Website

Get Prices

What Results Can You Expect From A ‘Fat Burner’?

It is widely accepted that the main way to lose unwanted body weight is to stick to a sensible and well-controlled diet and exercise program in which you’re burning slightly more calories than you’re ingesting. In other words, a sustained calorie deficit is key.

As we have already pointed out, there are no miracle pills out there that will work without hard work on your part.

If it sounds too good to be true, it typically is. Cutting fast like and getting into shape like the Pro’s requires commitment and discipline. Any top-level athlete will tell you there’s no shortcut. It all comes down to the basics.

However, that doesn’t mean you can make your weight loss journey a lot smoother, easier, and possibly even faster. This is where proven fat burner supplements come in. There are plenty of them on the market that provide ingredients to support your body as you look to lose weight and maintain that success long-term.

Our pick of the best weight loss supplements featured in this guide contain ingredients that may bring significant benefit and help to get you to your goals faster, when combined with the aforementioned lifestyle choices.

Side Effect Talk – Are Fat Burners Safe?

It is vital that you speak to a qualified professional before taking a new supplement for the first time. More so if you have a health condition or are taking any medications.

All of the supplements we’ve listed today contain ingredients that are commonly found in everyday foods and supplements, such as vitamins, minerals, amino acid, and herbal extracts. The products featured here all contain researched-backed ingredients in safe doses, so the risk of side effects is minimal.

That being said, some ingredients do have the potential to cause some unwanted reactions, which is why you need to do your own research into each of these substances.

If you have extreme caffeine sensitivity, then you will want to avoid excessive stimulant intake or supplements that contain stimulants altogether. In such cases, a stimulant-free fat burner can give you just as good results without the risk.

Some supplement companies will disclose potential side effects which may come from certain ingredients on the label of the product in question, so it’s always worth checking this information before trialing a new product.

Final Thoughts – Wrapping Things Up

There you have it, this was our guide to some of the best weight loss supplements on offer today.

We’ve walked you through some of the important things you need to know about products in this category, including who they are for and the benefits they can provide.

We currently rate Instant Knockout CUT as the best option all-around for both men and women. It has a tried and tested formula that, ever since its release in 2015, has remained on top, in no small part thanks to the manufacturer’s efforts in consulting with experts and keeping their formula updated according to the latest evidence.

Hourglass Fit is the ideal option for women who’re having issues with appetite control and mood swings, as it specializes in tackling both issues. Burn Lab Pro may also be a good choice if you’re looking for a low-stim option that improves the fat-burning effects of intermittent fasting.


  1. Weiss DJ, Anderton CR. Determination of catechins in matcha green tea by micellar electrokinetic chromatography. J Chromatogr A. 2003 Sep 5;1011(1-2):173-80. doi: 10.1016/s0021-9673(03)01133-6. PMID: 14518774. (source)
  2. Caitlin Mason, Liren Xiao, Ikuyo Imayama, Catherine Duggan, Ching-Yun Wang, Larissa Korde, Anne McTiernan, Vitamin D3 supplementation during weight loss: a double-blind randomized controlled trial, The American Journal of Clinical Nutrition, Volume 99, Issue 5, May 2014, Pages 1015–1025,

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