Best Fat Burner Supplements in 2022: Our Top 5 Picks

Best Fat Burner Supplements

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Tired of diet pills that don’t work? Here’s our top 5 weight loss supplements list (now updated for 2022)! In case you already aren’t experienced with them, fat burners are dietary supplements that help support the loss of weight by increasing your metabolism, reducing appetite, and helping your body turn fat into fuel.

Our top fat burners have all been thoroughly inspected to ensure they bring results, are safe, and are free of any suspect or artificial ingredients. Our criteria includes:

  • Sustainable, long-term weight loss results
  • 100% science-backed ingredients
  • Energy boost
  • Appetite reduction
  • Mood & focus support
  • Healthy for daily use
  • Brand trustworthiness

The following natural fat burners also work to enhance your workouts through energy support, which can be especially helpful when you’re trying to stay in a calorie deficit.

In this past year alone, we’ve reviewed over 30 fat burners on the market, comparing them against one another to see which one is the best bang for your buck. The result of our investigation has enabled us to recommend the following 5 fat burners on offer right now.

Our Recommendation: The 5 of The Best Fat Burners

Instant Knockout

  • Formulated for Pro Athletes

  • Elevate metabolism 

  • Reduce appetite

  • Fast-acting fat burn

  • Excellent reviews

Hourglass Fit

  • Specifically developed for women

  • Achieve toned muscles

  • Gain definition

  • Stimulant-free ingredient profile

  • Check price: hourglassfit.com

Burn Lab Pro

  • Cleanest quality stim-free fat burner

  • 100% transparent & free from fillers

  • Used by UFC Bantamweight Champ

  • Patented nutrition technology

  • Excellent bulk-buy deals

  • Check price: burnlabpro.com

Prime Shred

  • More ingredients

  • Larger doses & servings 

  • Potent hunger control

  • Premium-grade supplement

  • Maximum impact formula

  • Check price: primeshred.com

ShredCBD

  • 40mg of Pure CBD isolate per capsule

  • Works to enhance your exercise

  • cGMP approved and safety controlled

  • Promotes fat 'browning'

  • May improve your sleep & mood

  • Check price: shredcbd.com

What is a Weight Loss Supplement?

As we explained, weight loss supplements are over-the-counter food products typically consisting of different nutrients and herbs which have been shown to affect weight loss in one way or another.

For example, a combination of certain plant extracts within a supplement may produce a thermogenic effect, making your metabolism more efficient at burning calories.

So, if you’ve been struggling to stay below your daily caloric maintenance, a fat burner can help you burn those extra calories – giving you the edge needed to finally start getting results.

  • Not only that, there are ingredients in fat burners that work as natural appetite suppressants. For example, fibrous plants like Glucomannan are considered industry-leading appetite suppressants due to their ability to expand in your stomach and make you feel fuller. This results in fewer calories being consumed overall.

Some supplements also use clinical amounts of stimulants such as caffeine anhydrous. The reason is that stimulants make you more energized, boost your metabolism further, and suppress your appetite. When dosed correctly and taken with optimal serving frequency, natural stimulants can be one of the safest and most effective ways to accelerate weight loss. But there are also exceptions, like Yohimbine and Bitter Orange – we’ll warn you of these in our reviews.

Caffeineated fat burners represented by roasted and raw beans

As we’ve repeated, plant extracts are another common group of ingredients you’ll find in fat burners. Some of these have robust human evidence, and, some do not. We’ve done the legwork for you today by weeding through ineffective supplements to present you with the current highest-rated fat burners on the market.

The Top 5 Fat Burner Supplements in 2022

1. Instant Knockout CUT – Best Overall

Instant Knockout Cut

Instant Knockout is a premium, industry-leading fat burning supplement that can help you lose unwanted weight relatively fast. It was originally developed for MMA fighters by Roar Ambition, a specialist company based in the U.K. but operating worldwide.

This product boasts excellent testimonials and some of the best ratings out of any fat burner. It has been used by both men and women to burn fat in a healthy and natural way.

Effects that make Instant Knockout our #1 recommended thermogenic:

  • Fat loss results in 5-6 weeks
  • Contributes to a reduction in food cravings
  • Protects lean muscle tissue
  • Improves energy metabolism and mental focus

Ever since its launch in 2012, Instant Knockout has been regularly updated in accordance to the latest scientific research. Specifically, Instant Knockout’s makers look to update IKO every 6-12 months based on their consultations with nutritionists, pro athletes, and health experts.

We like this – it tells us that Roar Ambition puts continuous effort into giving us the best, most up-to-date fat burner.

Official website: instantknockout.com

Here is the full Instant Knockout Cut ingredients list:

Instant Knockout CUT Ingredients

We can see why so many people find cutting weight with IKO to be smooth and easy. It starts working almost right away.

The ingredients are all evidence-backed and dosed precisely to deliver safe and sustainable results. The combination of Glucomannan+caffeine works to reduce the appetite, along with giving you a clean source of energy that should last you the entire day.

Meanwhile, ingredients such as vitamin D, green tea extract, and cayenne pepper extract synergize to boost your metabolic speed, helping you to burn excess fat quicker. After about 3 weeks is when you should start noticing the first changes in your physique and around the belly, which makes Instant Knockout the fastest weight loss supplement we’ve seen.

If you keep going for 2-3 months with this product and a clean lifestyle you should see some impressive differences in your body.

One annoying thing about Instant Knockout is that you can only buy it directly from the manufacturer, and the price is premium, but it’s sort of expected from a product of this level of quality.

In each Instant Knockout bottle, you will find 120 capsules – providing a month’s supply.

Instant Knockout has a dosage of 1 capsule, 4 times per day. This is another thing that may look annoying a first, but it’s actually a clever way to dose a fat burner – it enables the beneficial ingredients to circulate in your system for longer.

Pros

  • Great value
  • Achieve a leaner physique
  • Premium formula with clinically dosed ingredients
  • Trusted by pro fighters and trainers
  • Safe and natural ingredient profile
  • Excellent bulk-buy deals with worldwide shipping

Cons

Instant Knockout Is Available On The Manufacturer’s Website

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2. Burn Lab Pro – Cleanest Quality Non-Caffenianted Fat Burner

Burn Lab Pro is a vegan, stim-free fat burner with one of the cleanest formulas we’ve seen.

Burn Lab Pro

Developed by the respected nutraceutical company Opti-Nutra, Burn Lab Pro is arguably just as effective as any premium fat burner, despite being low on caffeine.

It features 5 patented, optimally-dosed ingredients that help you:

  • Boost fat loss in the body
  • Increase thermogenesis
  • Preserve muscle tissue

One thing that separates Burn Lab Pro from the rest is its focus on protecting your muscle mass and maintaining energy levels when you’re low on calories. This is especially useful for people who do weight training and want to preserve as much lean muscle as possible when dieting.

Official website: burnlabpro.com

Who is Burn Lab Pro for? It’s for people who’re looking to maintain their lean muscle mass while burning fat, as well as for those who’re sensitive to stimulants or simply want to avoid unnecessary fillers or other synthetic ingredients – none of those are in Burn Lab Pro!

Here is the full ingredient list:

Burn Lab Pro Ingredients

In Burn Lab Pro you’ll find the essential trace mineral chromium, which contributes to healthy blood sugar levels. You may find that this reduces the frequency and intensity of sugar cravings. Cayenne pepper and Coleus Forskohlii, meanwhile, stimulate your to break down fat quicker and metabolize it for energy.

However, the main star in Burn Lab Pro is undoubtedly HMB calcium. It works by inhibiting the enzymes in your body that break down healthy muscle tissue. The result: you will be burning fat, not hard-earned muscle.

Burn Lab Pro’s ingredients are patented and some of the highest-quality we’ve seen. The ingredient dosages are on the lighter side, making Burn Lab Pro healthy for daily use.

Burn Lab Pro’s key advantage is its muscle-preserving effect. If you’re someone who follows intermittent fasting (IF) and trains on an empty stomach, Burn Lab Pro is the best option on this list.

Each bottle has 90 capsules, with the recommended dosage of 2-4 capsules before working out for maximum benefit.

Pros

  • Cleanest-quality formula available
  • Stimulant-free
  • Using patented, highly standardized compounds for stable, long-lasting effects
  • Protects from muscle loss
  • Works amazingly with intermittent fasting

Cons

  • The energy “kick” is not the same as with stimulant-containing fat burners

Burn Lab Pro Is Available On The Manufacturer’s Website

Get Prices

3. Hourglass Fit – The Best-Rated Women’s Fat Burner

Coming in 3rd is Hourglass Fit, another premium diet pill by Roar Ambition. Unlike IKO, this one is formulated for women who want to achieve the “Hourglass Figure” – a body with toned muscles and minimal body fat.

Hourglass Fit

Here’s the good news: Hourglass Fit works for anyone, no matter if you’re man or a women. While there are some differences in terms of our nutritional needs, when it comes to fat burning, the principles are almost the same.

Key advantages of Hourglass Fit:

  • Helps you to lose fat around your waist and get a sexy Hourglass physique
  • Powerful caffeine-free formula
  • Contains a massive 3g of the proven appetite suppressant glucomannan 

What Hourglass Fit excels in is its appetite-curbing effects. At the same time, it helps you burn body fat to reduce belly and waist size with its natural thermogenic ingredients.

  • Increase energy without stimulants
  • Tone up for a lean physique
  • Burn fat while controlling hunger

Official website: hourglassfit.com

Here is the full ingredient list:

Hourglass Fit Ingredients

Hourglass Fit is packed with studied and potent fat-burning compounds. For example, you will find a healthy dosage of cayenne extract, an evidence-backed thermogenic that heats up your body, boosts your metabolism, and makes you break down fat faster. There is also 3000mg of glucomannan, one of the best natural appetite suppressants on the market.

The appetite-curbing effect of Hourglass Fit is augmented by 5-HTP. A naturally occurring brain molecule shown to brighten mood and block hunger-triggering hormones, helping you to stay below your calorie limit. Essential nutrients such as B6, B12, and zinc are there to keep your hormones in balance for optimal fat burning.

Each bottle of Hourglass Fit contains 120 capsules, lasting 30 days. To get the maximum effects, you should take one capsule, four times per day. Again, this is an excellent serving schedule, just like with Instant Knockout.

Pros

  • Burn fat and reveal a toned figure
  • Effective reduction of hunger cravings with a high dose of glucomannan
  • Completely free of caffeine or other stimulants
  • Works for both genders, although the nutrients are specifically dosed for women’s metabolic needs

Cons

  • Only sells directly from the manufacturer
  • Some people will want a stronger stimulant “kick”

Hourglass Fit Is Available On The Manufacturer’s Website

Get Prices

4. ShredCBD – The Best CBD-Based Weight Loss Supplement

ShredCBD

ShredCBD is an innovative and side-effect-free solution to burning fat and feeling healthy. Developed by PFX Labs, CBD naturally activates your body’s endocannabinoid system (ECS). This makes supplementation extremely effective. It’s completely different from most fat burners on the market.

ShredCBD helps you “shred down” in 5 main ways:

  1. Triggers fat browning to stimulate the body to use fat as fuel
  2. Supports insulin sensitivity to prevent unwanted weight gain
  3. Substantially lowers cortisol, a stress hormone that promotes fat accumulation
  4. Improves mental well-being and sleep quality
  5. Reduces appetite and calorie consumption by interacting with brain’s ECS receptors

ShredCBD contains pure hemp isolate as its CBD, meaning it’s below 0.1% THC. This makes it non-psychoactive (doesn’t make you high), and completely legal in the USA and many other countries in the world.

Official website: shredcbd.com

In addition to CBD, the formula contains a synergistic combination of Green Tea and Garcinia Cambogia Extract to augment the overall fat burning effect. Green Tea and Garcinia are also packed with antioxidants that boost your immunity and keep you feeling leaner.

ShredCBD Ingredients
ShredCBD’s ingredient label.

What makes ShredCBD stand out in our eyes, is that it is just as effective for sleep, mood, and overall quality of life enhancement, as it is for weight loss. It is a kind of supplement you can use together with other supplements in your stack for all-around wellness support.

This is a quality product. Even after a couple of days, ShredCBD should lead to some noticeable improvements in your appetite, focus, and mood.

In terms of weight loss, you can expect ShredCBD to start showing results after around 30 days. Especially if you use CBD’s power to exercise and focus on a nutrient-packed diet.

Credits: supplementdevil.com

Effects over 2-6 weeks with ShredCBD:

  • Good amount of wight loss (as much as any stim-free fat burner)
  • Less desire to snack
  • More consistent energy throughout the day, without highs and lows
  • Most notable improvements in sleep and daily focus

ShredCBD is free of stimulants, which makes it a good choice if you don’t tolerate caffeine.

The Good

  • 40mg of pure CBD Isolate per serving (1200mg per bottle)
  • CBD alone has more potential benefits than many fat burner blends
  • Improves sleep quality & recovery
  • Free and Fast shipping in the USA
  • Free 24-page weight loss e-Book ($10 value, according to the manufacturer)

The Bad

  • Only sells in the USA
  • Premium price due to costly CBD isolate manufacturing

ShredCBD Is Available On The Manufacturer’s Website

Get Prices

5. Prime Shred

Prime Shred

PrimeShred is a male-focused weight loss supplement. It has been specifically formulated to help maximize the fat burning and muscle building effects of peak male hormone levels.

PrimeShred works by:

  • Accelerating the natural fat-burning process
  • Triggers the release of fat-burning hormones
  • Amplifies focus and energy release

Customers can get free worldwide shipping when buying Prime Shred. In addition, they offer deals such as buy 2 get 1 free, and buy 3 get two free. Looking at price-value, this is the best bulk-buy deal out of all fat burners in this guide.

Ingredients in Prime Shred

Prime Shred Ingredients

Prime Shred is utilizing the latest, up-to-date formula that features clinically studied and well-dosed ingredients.

The combination of L-Theanine and Caffeine gives you a nice, clean energy boost without side effects, whereas cayenne pepper, DMAE, and Green Coffee Bean stimulate your body to burn fat and also block hunger hormones. Rhodiola Rosea and L-Tyrosine combo works to prevent stress-induced fatigue to help you stay sharp mentally throughout the day.

Prime Shred’s formula is made in the USA, it’s vegan-friendly, and it’s free from GMO, soy, dairy, gluten, and artificial junk, making it a great option for health-conscious individuals.

Pros

  • Comprehensive, research-backed formula
  • Contributes to fat burning and appetite suppression
  • Increases mental focus and alertness
  • Highly effective at combating fatigue & adrenal burnout
  • Safe and healthy for daily use

Cons

  • Could use a better appetite suppressant
  • Only sells directly from primeshred.com

Prime Shred is Available on Official Website

– Check Price –

Final Thoughts on The Best Fat Burners in 2022

With a little research, you can easily find the ideal fat burning supplement for yourself. It is important to know that fat burner supplements, when using high-quality ingredients in studied dosages, are very safe and unlikely to cause side effects.

Our personal preference is without question Instant Knockout CUT. There is a reason why it’s been among market-leading fat burner supplements ever since its release in 2015. It is a tried and tested formula, and it works. Instant Knockout is not some outdated supplement made long ago and forgotten about. Its manufacturers consult with nutritionists and fitness experts to keep Instant Knockout updated in accordance to the latest weight loss research.

Hourglass Fit is the ideal weight loss supplement for women who struggle with appetite control and low energy during the day.

Burn Lab Pro is another solid option if you are sensitive to stimulants like caffeine. It works to enhance fat burning in a light and safe way, while also being highly effective at preserving muscle when you train on an empty stomach.

References, Literature, and Sources

  1. Weiss DJ, Anderton CR. Determination of catechins in matcha green tea by micellar electrokinetic chromatography. J Chromatogr A. 2003 Sep 5;1011(1-2):173-80. doi: 10.1016/s0021-9673(03)01133-6. PMID: 14518774. (source)
  2. Caitlin Mason, Liren Xiao, Ikuyo Imayama, Catherine Duggan, Ching-Yun Wang, Larissa Korde, Anne McTiernan, Vitamin D3 supplementation during weight loss: a double-blind randomized controlled trial, The American Journal of Clinical Nutrition, Volume 99, Issue 5, May 2014, Pages 1015–1025, https://doi.org/10.3945/ajcn.113.073734
  3. https://supplementdevil.com/fat-burner/best-fat-burners/
  4. https://www.thesportreview.com/health-and-fitness/best-fat-burner/

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